Naples is a city in Italy; it is the capital of the region of Campania and of the province of Naples. Known for its rich history, art, culture, architecture, music, and gastronomy, Naples has played an important role in the Italian peninsula and beyond for much of its existence, which began more than 2,800 years ago. Situated on the west coast of Italy by the Gulf of Naples, the city is located halfway between two volcanic areas, Mount Vesuvius and the Phlegraean Fields. Naples has the fourth-largest urban economy in Italy, after Milan, Rome and Turin. It is the world's 103rd-richest city by purchasing power, with an estimated 2011 GDP of US$83.6 billion. The port of Naples is one of the most important in Europe, and has the world's second-highest level of passenger flow, after the port of Hong Kong. The city has long been a major cultural centre with a global sphere of influence, particularly during the Renaissance and Enlightenment eras. In the immediate vicinity of Naples are numerous culturally and historically significant sites, including the Palace of Caserta and the Roman ruins ofPompeii and Herculaneum. Culinarily, it is synonymous with pizza, which originated in the city.

Málaga is a large city in the southern Spanish region of Andalucia and capital of the Malaga Province. The largest city on the Costa del Sol, Malaga has a typical Mediterranean climate and is also known as the birthplace of famous Spanish artist Pablo Picasso. The city offers beaches, hiking, architectural sites, art museums, excellent shopping and cuisine. While more laid back than Madrid or Barcelona, Malaga is still the center and transport hub for the hugely popular Costa del Sol region, which is flooded with tourists in the summer, and the city has certainly cashed in on the sun and sand, with lots of new construction as well as hotels and facilities geared to tourists. However, Malaga also offers some genuinely interesting historical and cultural attractions in its old city and its setting on the coast is still beautiful.

Barcelona – Spain's enchanting capital, second largest and most populous city. It is a huge city that vibrates with life, and there’s certainly not another city in the country to touch it for its sheer style, looks or energy. It is one of the world's leading tourist, economic, trade fair and cultural centers, and its influence in commerce, education, entertainment, media, fashion, science, and the arts all contribute to its status as one of the world's major global cities. Barcelona is home to masterpieces of many great architects – the most famous of which is Antoni Gaudí. 

Valencia is the most populous city of the Autonomous Community of Valencia and the third largest city in Spain, with a population of 809,267 in 2010. It is the 15th-most populous municipality in the European Union. It is integrated into an industrial area on the Costa del Azahar. Its historic centre is one of the largest in Spain, with approximately 169 hectares; this heritage of ancient monuments, views and cultural attractions makes Valencia one of the country's most popular tourist destinations!

Cagliari is an Italian municipality and the capital of the island of Sardinia, an autonomous region of Italy. Cagliari's Sardinian name ''Casteddu'' literally means castle. An ancient city with a long history, Cagliari has seen the rule of several civilisations. Under the buildings of the modern city there is a continuous stratification attesting to human settlement over the course of some five thousand years, from the Neolithic to today. Historical sites include the prehistoric domus de janas, very damaged by cave activity, a large Carthaginian era necropolis, a Roman era amphitheatre, a Byzantine basilica, three Pisan-era towers and a strong system of fortification that made the town the core of Spanish Habsburg imperial power in the western Mediterranean Sea. Its natural resources have always been its sheltered harbour, the often powerfully fortified hill of Monti Castru, the modern Casteddu, the salt from its lagoons, and, from the hinterland, wheat from the Campidano plain and silver and other ores from the Iglesiente mines. Today the city is a regional cultural, educational, political and artistic centre, known for its diverse Art Nouveau architecture and several monuments. It is also Sardinia's economic and industrial hub, having one of the biggest ports in the Mediterranean Sea, an international airport, and the 106th highest income level in Italy (among 8,092 comuni), comparable to that of several northern Italian cities. It is also the seat of the University of Cagliari, founded in 1607, and of the Primate Roman Catholic archdiocese of Sardinia, since the 5th century AD.

Cartagena is a Spanish city and a majornaval station located in the Region of Murcia, by the Mediterranean coast, south-eastern Spain. The metropolitan area of Cartagena, known as Campo de Cartagena, has a population of 409,586 inhabitants. Cartagena has been inhabited for over two millennia, being founded around 227 BC by the Carthaginian Hasdrubal the Fair as Qart Hadasht, the same name as the original city of Carthage. Much of the historical weight of Cartagena in the past goes to its coveted defensive port, one of the most important in the western Mediterranean. As far back as the 16th century it was one of the most important naval ports in Spain, together with Ferrol in the North. It is still an important naval seaport, the main military haven of Spain, and is home to a large naval shipyard. The confluence of civilizations as well as its strategic harbour, together with the rise of the local mining industry is manifested by a unique artistic heritage, with a number of landmarks such as the Roman Theatre, the second largest of the Iberian Peninsulaafter the one in Mérida, an abundance of Phoenician, Roman, Byzantine and Moorish remains, and a plethora of Art Nouveaubuildings, a result of the bourgeoisie from the early 20th century. Cartagena is now established as a major cruise ship destination in the Mediterranean and an emerging cultural focus. It is the first of a number of cities that eventually have been named Cartagena, most notably Cartagena de Indias (Cartagena of the Indies) in Colombia.

Civitavecchia is a town and comune of the Metropolitan City of Rome in the central Italian region of Lazio. A sea port on the Tyrrhenian Sea, the name ''Civitavecchia'' means "ancient town". The modern city was built over a pre-existing Etruscan settlement. The massive Forte Michelangelo was first commissioned from Donato Bramante by Pope Julius II, to defend the port of Rome. The upper part of the "maschio" tower, however, was designed by Michelangelo, whose name is generally applied to the fortress. North of the city at Ficoncella are the Terme Taurine baths frequented by Romans and still popular with the Civitavecchiesi. The modern name stems from the common fig plants among the various pools. And also next to the town is the location of the cruise ship docks. All major cruise lines start and end their cruises at this location, and others stop for shore excursion days that allow guests to see Rome and Vatican sights, which are ninety minutes away.